Effects of high-level exposure to lead on NK cell activity and T-lymphocyte functions in workers
- 1 June 1997
- journal article
- research article
- Published by SAGE Publications in Human & Experimental Toxicology
- Vol. 16 (6) , 311-314
- https://doi.org/10.1177/096032719701600603
Abstract
1 NK and T cell functions were measured in peripheral blood lymphocytes of workers occupationally exposed to lead. 2 No differences were found in these functions even in those workers with higher levels of blood and urine lead and urinary δ-ALA than the currently accepted biological limit values as compared to controls. 3 We conclude that high chronic exposure to lead is not associated with an impairment or either T- or NK cell functions in man.Keywords
This publication has 17 references indexed in Scilit:
- Effects of acute lead ingestion and diet on antibody and T-cell-mediated immunity in Japanese quailArchives of Environmental Contamination and Toxicology, 1995
- Immunoglgbulin Levels and Cellular Immune Function in Lead Exposed WorkersImmunopharmacology and Immunotoxicology, 1994
- Phenotypic Aberrations of CD3+ and CD4+ Cells and Functional Impairments of Lymphocytes at Low-Level Occupational Exposure to LeadClinical Immunology and Immunopathology, 1993
- Early effects of lead on bone marrow cell responsiveness in mice challenged with Listeria monocytogenes*1Fundamental and Applied Toxicology, 1991
- Analysis of heavy metal immunotoxicity by multiparameter flow cytometry: Correlation of flow cytometry and immune function data in B6CF1 miceInternational Journal of Immunopharmacology, 1987
- Failure of inorganic lead exposure to impair natural killer (NK) cell and T lymphocyte function in ratsToxicology Letters, 1986
- The effect of lead and polychlorinated biphenyl exposure on rat natural killer cell cytotoxicityInternational Journal of Immunopharmacology, 1985
- The effects of heavy metals on [3H]thymidine uptake in lymphocytesToxicology and Applied Pharmacology, 1978
- Decreased antibody formation in mice exposed to leadNature, 1974
- Lead Aggravates Viral Disease and Represses the Antiviral Activity of Interferon InducersEnvironmental Health Perspectives, 1974