Quantitive dependence of N-methyl inversion barriers in six-membered rings on electronic and steric effects. Direct observation of the conformational equilibria in tetrahydro-1,3-oxazines and hexahydropyrimidines

Abstract
Low-temperature 1H n.m.r. spectra of N-methyl and N,C-polymethyl derivatives of tetrahydro-1,3-oxazine and hexahydropyrimidine allow calculation of conformational equilibria and the rationalisation of steric and electronic effects on N-methyl inversion barriers.

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