A Convenient and Regioselective Synthesis of 4-Trifluoromethylpyridines
- 1 November 1997
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1997 (11) , 1321-1324
- https://doi.org/10.1055/s-1997-1354
Abstract
Trifluoromethyl-substituted β-diketones regioselectively react with primary enamines such as β-aminocrotononitrile and ethyl β-aminocrotonate, providing moderate to good yields of 4-trifluoro-methylpyridines.Keywords
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