Satisfactorily attenuated and protective mutants derived from a partially attenuated cold-passaged respiratory syncytial virus mutant by introduction of additional attenuating mutations during chemical mutagenesis
- 31 December 1994
- Vol. 12 (8) , 691-699
- https://doi.org/10.1016/0264-410x(94)90218-6
Abstract
No abstract availableKeywords
This publication has 29 references indexed in Scilit:
- A comparison in chimpanzees of the immunogenicity and efficacy of live attenuated respiratory syncytial virus (RSV) temperature-sensitive mutant vaccines and vaccinia virus recombinants that express the surface glycoproteins of RSVVaccine, 1993
- Evaluation in chimpanzees of vaccinia virus recombinants that express the surface glycoproteins of human respiratory syncytial virusVaccine, 1990
- Immunization of cotton rats with the fusion (F) and large (G) glycoproteins of respiratory syncytial virus (RSV) protects against RSV challenge without potentiating RSV diseaseVaccine, 1989
- Characterization of a Novel Human Respiratory Syncytial Virus Chimeric FG Glycoprotein Expressed Using a Baculovirus VectorJournal of General Virology, 1989
- The Association of the Temperature-Sensitive Phenotype with Viral Attenuation in Animals and Humans: Implications for the Development and Use of Live Virus VaccinesClinical Infectious Diseases, 1979
- Respiratory-Syncytial-Virus Infections, Reinfections and ImmunityNew England Journal of Medicine, 1979
- Evaluation of five temperature-sensitive mutants of respiratory syncytial virus in primates: II. Genetic analysis of virus recovered during infectionJournal of Medical Virology, 1978
- Evaluation of five temperature‐sensitive mutants of respiratory syncytial virus in primates: I. Viral shedding, immunologic response, and associated illnessJournal of Medical Virology, 1978
- Evaluation of a live, attenuated respiratory syncytial virus vaccine in infantsThe Journal of Pediatrics, 1976
- Low-temperature-grown RS virus in adult volunteersPublished by American Medical Association (AMA) ,1968