Schizophrenia Susceptibility and HL-A Antigen

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Abstract
The phenotype frequencies of HL-A specificities have been investigated in 47 chronic schizophrenics subdivided in an older and a younger group. The frequency of HL-A 9 was significantly increased in the psychotics as compared to a reference group of 1,263 healthy blood donors, pregnant women and potential kidney donors. Deviations in frequency were also found concerning W 19 and HL-A 5. As HL-A 9 was mainly found in the older group of schizophrenics, it is suggested that HL-A 9 might be associated to some form of schizophrenia with a chronic course.

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