Comparative studies of spermatogenesis in fertile and subfertile men.
Open Access
- 1 February 1981
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 34 (2) , 145-150
- https://doi.org/10.1136/jcp.34.2.145
Abstract
Testicular biopsy specimens from 16 fertile and 10 subfertile men with normal male karyotype were studied quantitatively to provide histological and cytogenetic data for a basis of reference in assessing abnormalities of spermatogenesis. Histological studies included estimation of the proportion and activity of germinal epithelium and an assessment of tubular morphology. In cytogenetic preparations, counts were made of cells at different stages of meiosis. Studies of cells at diakinesis included chiasma counts and percentage of cells with dissociated sex chromosomes. One fertile and six subfertile men showed decreased germinal activity; the six subfertile men also had decreased MII/MI ratios. Other findings were similar in the two groups.This publication has 12 references indexed in Scilit:
- SEMINIFEROUS TUBULE HYPERCURVATURE: A NEWLY RECOGNISED COMMON SYNDROME OF HUMAN MALE INFERTILITYThe Lancet, 1979
- Cytogenetics and infertility in man: II. Testicular histology and meiosis.Annals of Human Genetics, 1976
- STUDIES ON MEIOTIC CHROMOSOMES IN INFERTILE MEN AND CONTROLS WITH NORMAL KARYOTYPESReproduction, 1973
- The frequency and distribution of chiasmata in manAnnals of Human Genetics, 1973
- Quantification of human seminiferous epithelium. 3. Histological studies in 44 infertile men with normal chromosome complements.1973
- QUANTIFICATION OF HUMAN SEMINIFEROUS EPITHELIUMReproduction, 1973
- Centromere staining at meiosis in manHuman Genetics, 1973
- Testicular Biopsy Score Count – A Method for Registration of Spermatogenesis in Human Testes: Normal Values and Results in 335 Hypogonadal MalesHormone Research in Paediatrics, 1970
- STUDIES ON HUMAN MEIOTIC CHROMOSOMES FROM TESTICULAR TISSUEThe Lancet, 1966
- An Air-Drying Method for Meiotic Preparations from Mammalian TestesCytogenetic and Genome Research, 1964