Abstract
ALTHOUGH primary amebic meningoencephalitis has been previously described in the Journal,1 , 2 the events leading to recognition of this entity illustrate a common phenomenon of medicine — namely, how isolated and apparently unrelated observations eventually merge into a comprehensible picture of new information. The beginning goes back to the mid-fifties, when several different groups of virologists encountered amebas in cultures of monkey-kidney tissue3 4 5 that were used extensively at that time. The organisms were classified as members of the genus acanthamoeba, a variety that live freely in the environment, in contrast to the parasitic amebas (including the human varieties), which normally . . .