Quantitative Evaluation of Chromatograms By Digital Computers
- 1 November 1969
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Chromatographic Science
- Vol. 7 (11) , 680-684
- https://doi.org/10.1093/chromsci/7.11.680
Abstract
Accurate peak area measurement is a fundamental requirement of gas chromatography. The accuracy of area recovery by on-line dedicated computers was investigated. The influence of scan rate, data smoothing, peak detection and baseline correction on peak area recovery was determined. Programs were evaluated which use the inherent flexibility of the computer to update smoothing, peak detection and baseline correction parameters to match the changing requirements during the chromatographic analysis.Keywords
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