An Extensive Interaction Interface between Thrombin and Factor V Is Required for Factor V Activation
Open Access
- 1 January 2001
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 276 (27) , 25143-25149
- https://doi.org/10.1074/jbc.m011324200
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- Electrostatic Steering and Ionic Tethering in the Formation of Thrombin−Hirudin Complexes: The Role of the Thrombin Anion-Binding Exosite-IBiochemistry, 2001
- Platelet Glycoprotein Ibα Binds to Thrombin Anion-binding Exosite II Inducing Allosteric Changes in the Activity of ThrombinJournal of Biological Chemistry, 2001
- Demonstration of Exosite I-Dependent Interactions of Thrombin with Human Factor V and Factor Va Involving the Factor Va Heavy Chain: Analysis by Affinity Chromatography Employing A Novel Method for Active-Site-Selective Immobilization of Serine ProteinasesBiochemistry, 1998
- Localization of the Heparin-Binding Site of Glia-Derived Nexin/Protease Nexin-1 by Site-Directed MutagenesisBiochemistry, 1994
- Interaction of hirudin with the dysthrombins Quick I and IIBiochemistry, 1991
- The Structure of a Complex of Recombinant Hirudin and Human α-ThrombinScience, 1990
- Identification of the primary structural defect in the dysthrombin thrombin Quick I: substitution of cysteine for arginine-382Biochemistry, 1988
- The effect of thrombomodulin on the cleavage of fibrinogen and fibrinogen fragments by thrombinEuropean Journal of Biochemistry, 1987
- Identification of regions of .alpha.-thrombin involved in its interaction with hirudinBiochemistry, 1987
- Human .alpha.-thrombin binding to nonpolymerized fibrin-sepharose: evidence for an anionic binding regionBiochemistry, 1985