Dicentric Y Chromosome Without Evidence of Mosaicism in an Azoospermic Male
- 1 February 1996
- journal article
- case report
- Published by Taylor & Francis in Scandinavian Journal of Urology and Nephrology
- Vol. 30 (1) , 75-76
- https://doi.org/10.3109/00365599609182354
Abstract
A phenotypically male of dicentric Y chromosome with no evidence of sex chromosomal mosaicism is reported. Staining of fluorescence in situ hybridization using Y chromosome centromere-specific DNA probe showed the presence of two bright fluorescent spots in Y chromosome. Testicular histology revealed maturation arrest at the stage of primary spermatocyte. It is suggested that structural anomaly of the Y chromosome is related to the disturbance of spermatogenesis.Keywords
This publication has 11 references indexed in Scilit:
- Deletion of specific sequences or modification of centromeric chromatin are responsible for Y chromosome centromere inactivationHuman Genetics, 1990
- Y;autosome translocations and mosaicism in the aetiology of 45,X maleness: assignment of fertility factor to distal Yq11Human Genetics, 1988
- Dicentric chromosomes and the inactivation of the centromereHuman Genetics, 1986
- Chromosome studies in 952 infertile males with a sperm count below 10 million/mlHuman Genetics, 1985
- Chromosome studies in 496 infertile males with a sperm count below 10 million/mlHuman Genetics, 1984
- Dicentric i(Yq) chromosome and azoospermiaAmerican Journal of Medical Genetics, 1983
- Localisation of male determining factors in man: a thorough review of structural anomalies of the Y chromosome.Journal of Medical Genetics, 1981
- Mapping the Locus of the H-Y Gene on the Human Y ChromosomeScience, 1977
- Cytological findings of 10 cases with i(Xq) and one with dic(X)(qter?cen?p22:: p11?qte)Human Genetics, 1977
- Four new cases of dicentric Y chromosomesHuman Genetics, 1977