Norvaline accumulation by regulatory mutants of Serratia marcescens.
- 1 January 1977
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 30 (1) , 111-117
- https://doi.org/10.7164/antibiotics.30.111
Abstract
A gene coding for desensitized L-threonine dehydratase was transduced with phage PS20 into a leucine accumulator of S. marcescens Sr41. The transductant converted L-threonine to .alpha.-ketobutyrate, a precursor of norvaline and isoleucine. An isoleucine-valine auxotroph of the transductant accumulated large amount of norvaline from L-threonine and from D-threonine.This publication has 1 reference indexed in Scilit:
- Methods for the production of mutants suitable as amino acid fermentation organismsBiotechnology & Bioengineering, 1965