Conformationally Constrained Analogues of Diacylglycerol. 10. Ultrapotent Protein Kinase C Ligands Based on a Racemic 5-Disubstituted Tetrahydro-2-furanone Template
- 1 January 1996
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 39 (1) , 19-28
- https://doi.org/10.1021/jm950276v
Abstract
No abstract availableKeywords
This publication has 9 references indexed in Scilit:
- Crystal structure of the Cys2 activator-binding domain of protein kinase Cδ in complex with phorbol esterPublished by Elsevier ,1995
- Protein kinase C: is its pivotal role in cellular activation over-stated?Trends in Pharmacological Sciences, 1994
- Conformationally constrained analogues of diacylglycerol. 6. Changes in PK-C binding affinity for 3-O-acyl-2-deoxy-L-ribonolactones bearing different acyl chains.Bioorganic & Medicinal Chemistry Letters, 1994
- Synthesis of carbon-14 and tritium analogues of the phospholipid antitumor agent SDZ 62-834 ziJournal of Labelled Compounds and Radiopharmaceuticals, 1992
- Cooperation of cyclodextrin and alkali-metal halide for regioselective cleavage of ribonucleoside 2',3'-cyclic phosphatesJournal of the American Chemical Society, 1992
- The stereospecific activation of protein kinase CBiochemical and Biophysical Research Communications, 1984
- Characterization of a specific phorbol ester aporeceptor in mouse brain cytosol.Proceedings of the National Academy of Sciences, 1983
- Identification of high-affinity phorbol ester receptor in cytosol of EL4 thymoma cells: requirement for calcium, magnesium, and phospholipids.Proceedings of the National Academy of Sciences, 1983
- The Cambridge Crystallographic Data Centre: computer-based search, retrieval, analysis and display of informationActa Crystallographica Section B: Structural Science, Crystal Engineering and Materials, 1979