A study of lymph nodes draining colorectal cancer using a two-stage inhibition of leucocyte migration technique.
Open Access
- 1 April 1975
- Vol. 16 (4) , 290-297
- https://doi.org/10.1136/gut.16.4.290
Abstract
A two-stage technique for leucocyte migration inhibition has been developed which demonstrates the sensitization of lymph node lymphocytes to colorectal tumour extract. The studies have confirmed that some lymph nodes draining colorectal carcinomata contain sensitized lymphocytes. However, the degree of lymphocyte sensitization to tumour extract does not seem greater than that seen in lymph nodes of the small bowel mesentery or of the peripheral blood.Keywords
This publication has 23 references indexed in Scilit:
- Inhibition of leucocyte migration by tumour-associated antigens of the colon and rectumGut, 1973
- Phytohaemagglutinin-stimulated transformation of peripheral and lymph-node lymphocytes in patients with gastro-intestinal cancerBritish Journal of Surgery, 1973
- Carcinoembryonic Antigen in FaecesBMJ, 1972
- Immunologic Competence of Regional Lymph Nodes in Patients with Mammary CancerAnnals of Surgery, 1971
- THE DISTRIBUTION OF 51CR-LABELED LYMPHOCYTES INTO ANTIGEN-STIMULATED MICEThe Journal of Experimental Medicine, 1971
- REDUCED LYMPHOCYTE TRANSFORMATION IN BREAST CANCERThe Lancet, 1971
- Effect of autologous mammary tumour extracts on human leukocyte migration in vitroInternational Journal of Cancer, 1970
- The cellular immune response to primary sarcomata in rats I. The significance of large basophilic cells in the thoracic duct lymph following antigenic challengeProceedings of the Royal Society of London. B. Biological Sciences, 1969
- The cellular immune response to primary sarcomata in rats II. Abnormal responses of nodes draining the tumourProceedings of the Royal Society of London. B. Biological Sciences, 1969
- Results of Simple Mastectomy without Irradiation in the Treatment of Operative Stage I Cancer of the BreastAnnals of Surgery, 1968