GENETICS OF CYCLOHEXIMIDE RESISTANCE IN TETRAHYMENA

Open Access

1 October 1977

journal article
research article
Published by Oxford University Press (OUP) in Genetics

Vol. 87 (2) , 275-284
https://doi.org/10.1093/genetics/87.2.275

Abstract

Cycloheximide resistance in Tetrahymena is inducible by mutagenesis. Two mutations, isolated independently from genetically different strains, were analyzed. The two mutations, Chx-1 and Chx-2, were found to be alleles at the same locus. A specific analysis is presented which may serve as a model for strategies employing an independent manipulation of the micro- and macro-nuclei of this organism for genetic studies.

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