Synthesis and properties of human γ‐lipotropin
- 1 July 1982
- journal article
- research article
- Published by Wiley in International Journal of Peptide and Protein Research
- Vol. 20 (1) , 87-92
- https://doi.org/10.1111/j.1399-3011.1982.tb02657.x
Abstract
The synthesis of human .gamma.-lipotropin by the solid-phase method is described. The synthetic product was characterized by its migration factor in partition chromatography on Sephadex G-50, paper electrophoresis, polyacrylamide gel electrohoresis, TLC, high performance liquid chromatography, end group determination, peptide mapping of a tryptic digest and amino acid analyses of acid enzymic digests. The synthetic material is identical to natural human .gamma.-lipotropin when assayed against natural human .beta.-lipotropin for lipolytic activity in rabbit fat cells.Keywords
This publication has 30 references indexed in Scilit:
- HUMAN SOMATOTROPINInternational Journal of Peptide and Protein Research, 2009
- ISOLATION, CHARACTERIZATION AND AMINO ACID SEQUENCE OF β‐LIPOTROPIN FROM HUMAN PITUITARY GLANDSInternational Journal of Peptide and Protein Research, 1981
- Synthesis and biological activity of camel and bovine .beta.-melanotropinsJournal of Medicinal Chemistry, 1976
- Identification of two related pentapeptides from the brain with potent opiate agonist activityNature, 1975
- Adrenocorticotropins. 44. Total synthesis of the human hormone by the solid-phase methodJournal of the American Chemical Society, 1973
- Protection of tyrosine in solid-phase peptide synthesisThe Journal of Organic Chemistry, 1973
- Use of N.alpha.,Nim-bis(tert-butyloxycarbonyl)histidine and N.alpha.-2-(p-biphenylyl)isopropyloxycarbonyl-Nim-tert-butyloxycarbonylhistidine in the solid-phase synthesis of histidine-containing peptidesJournal of the American Chemical Society, 1972
- Derivate von L‐Methionin‐sulfoxyd und ihre Verwendung für PeptidsynthesenHelvetica Chimica Acta, 1961
- The Isolation, Characterization and Amino Acid Sequence of a Melanocyte-Stimulating Hormone from Bovine Pituitary GlandsJournal of the American Chemical Society, 1957
- Chromatography of Proteins. I. Cellulose Ion-exchange AdsorbentsJournal of the American Chemical Society, 1956