Garlic: Its Anticarcinogenic and Antitumorigenic Properties
- 27 April 2009
- journal article
- review article
- Published by Oxford University Press (OUP) in Nutrition Reviews
- Vol. 54 (11) , S82-S86
- https://doi.org/10.1111/j.1753-4887.1996.tb03823.x
Abstract
Overall, several investigations indicate that garlic and its organic allyl sulfur components inhibit the cancer process. Furthermore, these studies reveal that the benefits of garlic are not limited to a specific species, a particular tissue, or a specific carcinogen. Finally, odor is not a prerequisite for the protection provided by garlic against the initiation of chemical carcinogenesis. Although the water-soluble compound S-allyl cysteine is effective in reducing the risk of chemically induced tumors in experimental animals, it has no effect on established tumors. However, oil-soluble compounds such as diallyl disulfide are effective in reducing the proliferation of neoplasms. Although the evidence supports the benefits of garlic, additional evidence is needed to determine the quantity needed by humans to minimize cancer risk.Keywords
This publication has 22 references indexed in Scilit:
- Diallyl disulfide inhibits the proliferation of human tumor cells in cultureBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1996
- Diagnosis of polymorphisms in carcinogen-activating and inactivating enzymes and cancer susceptibility-a reviewGene, 1995
- Vegetables, Fruit, and Colon Cancer in the lowa Women's Health StudyAmerican Journal of Epidemiology, 1994
- Reducing the Risk of CancerPublished by Springer Nature ,1994
- Can garlic reduce levels of serum lipids? a controlled clinical studyThe American Journal of Medicine, 1993
- Garlic and its significance for the prevention of cancer in humans: a critical viewBritish Journal of Cancer, 1993
- Inhibitory effect of diet related sulphydryl compounds on the formation of carcinogenic nitrosaminesCancer Letters, 1992
- Allium Vegetables and Reduced Risk of Stomach CancerJNCI Journal of the National Cancer Institute, 1989
- Effects of organosulfur compounds from garlic and onions on benzo[a]pyrene-induced neoplasia and glutathione S-transferase activity in the mouseCarcinogenesis: Integrative Cancer Research, 1988
- Allium sativum (garlic) — A natural antibioticPublished by Elsevier ,1983