Dihydropyridines in synthesis and biosynthesis. I. Secodine and precursors of dehydrosecodine

1 February 1979

journal article
research article
Published by Canadian Science Publishing in Canadian Journal of Chemistry

Vol. 57 (3) , 289-299
https://doi.org/10.1139/v79-048

Abstract

A synthesis of 16,17-dihydrosecodin-17-ol and of secodine is described. Various indole derivatives were elaborated to a series of pyridinium salts, potential precursors for 1,2- and 1,6-dihydropyridine compounds exemplifying the proposed biointermediate dehydrosecodine [Catharanthus roseus alkaloid synthesis].