Pitfalls of reductionism in the design of peptide-based vaccines

This publication has 13 references indexed in Scilit:

• Neutralization of measles virus wild-type isolates after immunization with a synthetic peptide vaccine which is not recognized by neutralizing passive antibodies
  Journal of General Virology, 2000
• Molecular design versus empirical discovery in peptide-based vaccines. Coming to terms with fuzzy recognition sites and ill-defined structure–function relationships in immunology
  Vaccine, 1999
• Crossreactivity of mimotopes and peptide homologues of a sequential epitope with a monoclonal antibody does not predict crossreactive immunogenicity
  Vaccine, 1999
• Biosensors and the search for structure-activity correlations
  Journal of Molecular Recognition, 1999
• Sequences and topology From sequence to structure to function
  Current Opinion in Structural Biology, 1999
• Structure-based drug design
  Current Opinion in Biotechnology, 1998
• Protein folds and functions
  Published by Elsevier ,1998
• Understanding Science: Why Causes Are Not Enough
  Philosophy of Science, 1998
• Structure-Based Strategies for Drug Design and Discovery
  Science, 1992
• The Protection: The Unit of Humoral Immunity Selected by Evolution
  Immunological Reviews, 1990