Serine Derivative with Antitumor Activity
- 4 March 1960
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 131 (3401) , 666
- https://doi.org/10.1126/science.131.3401.666
Abstract
The sodium salt of N-dichloroacetyl-DL-serine depresses the growth of sarcoma-37 in mice, causing complete regressions of the tumor. The compound is nontoxic to mice in doses up to 4 gm/kg of body weight. The animals do not lose body weight and show no alteration in the formed elements of the blood or in hemoglobin content.Keywords
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