RNA silencing in plants
Top Cited Papers
- 15 September 2004
- journal article
- review article
- Published by Springer Nature in Nature
- Vol. 431 (7006) , 356-363
- https://doi.org/10.1038/nature02874
Abstract
There are at least three RNA silencing pathways for silencing specific genes in plants. In these pathways, silencing signals can be amplified and transmitted between cells, and may even be self-regulated by feedback mechanisms. Diverse biological roles of these pathways have been established, including defence against viruses, regulation of gene expression and the condensation of chromatin into heterochromatin. We are now in a good position to investigate the full extent of this functional diversity in genetic and epigenetic mechanisms of genome control.Keywords
This publication has 85 references indexed in Scilit:
- MicroRNAsCell, 2004
- Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domainNature, 2003
- ARGONAUTE4 Control of Locus-Specific siRNA Accumulation and DNA and Histone MethylationScience, 2003
- Regulation of Heterochromatic Silencing and Histone H3 Lysine-9 Methylation by RNAiScience, 2002
- RNA-directed transcriptional gene silencing in plants can be inherited independently of the RNA trigger and requires Met1 for maintenanceCurrent Biology, 2001
- Transcriptional silencing and promoter methylation triggered by double-stranded RNAThe EMBO Journal, 2000
- A Species of Small Antisense RNA in Posttranscriptional Gene Silencing in PlantsScience, 1999
- A Similarity Between Viral Defense and Gene Silencing in PlantsScience, 1997
- Plants combat infection by gene silencingNature, 1997
- RNA-directed de novo methylation of genomic sequences in plantsCell, 1994