USE OF ALFENTANIL WITH PROPOFOL FOR NASOTRACHEAL INTUBATION WITHOUT NEUROMUSCULAR BLOCK
Open Access
- 1 January 1993
- journal article
- clinical trial
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 70 (1) , 89-91
- https://doi.org/10.1093/bja/70.1.89
Abstract
We have investigated the effect of augmentation of propofol with alfentanil for nasotracheal intubation without neuromuscular block in 60 patients undergoing short elective maxillo-facial procedures as outpatients. After administration of glycopyrronium 5 fig kg−1 i.v., anaesthesia was induced with propofol 2.5 mg kg−1, or alfentanil 20 μg kg−1 and profopol 2.5 mg kg−1. The alfentanil group had improved jaw relaxation (P < 0.001) and vocalcord conditions (P < 0.005). Tracheal intubation was successful in 83% of patients receiving alfentanil, and in 73% of patients receiving propofol only. This difference was not significant. The cardiovascular response to intubation was attenuated in the alfentanil group. (Br. J. Anaesth. 1993; 70: 89–91)Keywords
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