Abstract
To establish the ultrastructural features of Leydig cells 50 biopsies of prepubertal human cryptorchid testes were examined. Light microscopic and EM observations reveal the presence of 2 types of interstitial cells distinguishable on the basis of the peculiar ultrastructure characteristics of the nucleus and cytoplasm. These 2 types of interstitial cells seem to represent different stages of cell differentiation. There are fibroblast-like cells and cells corresponding to Leydig cells. It may be inferred that the fibroblast-like cells are the precursor cells of the Leydig cells.