Differential Effects of Lysergic Acid and Sodium Amytal on Immediate Memory and Expressive Movement

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Abstract
This investigation deals with relationships of sodium amytal and lysergic acid (LSD) to measures of immediate memory and expressive movement as a function of exposure time. Significant differences in learning and expressive movement had been obtained previously between neurotics and schizophrenics (3, 4). The extent of these differences posed the problem why memory disturbance, as in the test, is clinically not more obvious in schizophrenics than in neurotics. It was thought that accidentally favourable conditions had been used, either in difficulty of task or in exposure time, to produce the results. The decision was taken to vary the exposure time in a pilot experiment, using LSD in normals to represent schizophrenic-like symptoms.