The Effect of Hydroxyethyl Starch on In Vitro Platelet and Granulocyte Function
- 10 September 1975
- journal article
- Published by Wiley in Transfusion
- Vol. 15 (5) , 473-475
- https://doi.org/10.1046/j.1537-2995.1975.15576082223.x
Abstract
The effect of hydroxyethyl starch (HES) on granulocyte and platelet functions was assessed. No alteration of granulocyte viability, morphology, phagocytic ability, or bactericidal capacity was detected after incubation with 6 per cent HES at 25 C for two hours. Platelet morphology, size distribution, aggregation, nucleotide and serotonin release, and platelet factor-3 availability were also unchanged after exposure to HES. It is concluded that HES has no adverse effect on cell function and appears to be a suitable adjuvant agent for blood cell component collection.Keywords
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