Perturbation of Endoplasmic Reticulum Homeostasis Facilitates Prion Replication
Open Access
- 27 April 2007
- journal article
- research article
- Published by Elsevier
- Vol. 282 (17) , 12725-12733
- https://doi.org/10.1074/jbc.m611909200
Abstract
No abstract availableKeywords
This publication has 73 references indexed in Scilit:
- Conditions of Endoplasmic Reticulum Stress Favor the Accumulation of Cytosolic Prion ProteinJournal of Biological Chemistry, 2006
- Cellular tolerance of prion protein PrP in yeast involves proteolysis and the unfolded protein responseBiochemical and Biophysical Research Communications, 2006
- Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS modelProceedings of the National Academy of Sciences, 2006
- Gene expression profiling of the preclinical scrapie-infected hippocampusBiochemical and Biophysical Research Communications, 2005
- Caspase-12 cleavage and increased oxidative stress during motoneuron degeneration in transgenic mouse model of ALSBiochemical and Biophysical Research Communications, 2004
- Mutant PrP Is Delayed in Its Exit from the Endoplasmic Reticulum, but Neither Wild-type nor Mutant PrP Undergoes Retrotranslocation Prior to Proteasomal DegradationJournal of Biological Chemistry, 2003
- Stimulation of PrPC Retrograde Transport toward the Endoplasmic Reticulum Increases Accumulation of PrPSc in Prion-infected CellsJournal of Biological Chemistry, 2002
- IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNANature, 2002
- XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription FactorCell, 2001
- The Chaperone Protein BiP Binds to a Mutant Prion Protein and Mediates Its Degradation by the ProteasomeJournal of Biological Chemistry, 2000