P760 and P775: MRI contrast agents characterized by new pharmacokinetic properties
- 1 August 1999
- journal article
- Published by Springer Nature in Magnetic Resonance Materials in Physics, Biology and Medicine
- Vol. 8 (3) , 172-176
- https://doi.org/10.1007/bf02594595
Abstract
Rationale and objectives: In this paper we discuss novel MR imaging blood pool agents characterized by new pharmacokinetic properties.Methods: The pharmacokinetics of the products were studied in a rabbit model. The potential of these new products was demonstrated in experimental MR imaging.Results and conclusion: Three main classes of blood pool agents have been defined and characterized according to their pharmacokinetic properties: low diffusion agents, rapid clearance blood pool agents, slow clearance blood pool agents. Each kind of blood pool agent is expected to have different diagnostic applications.Keywords
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