Synthesis and characterization of Sodium cis-dichlorochenodeoxycholylglycinato(O,N) platinum(II) – Cytostatic activity

1 January 1999

journal article
Published by Springer Nature in BioMetals

Vol. 12 (3) , 283-290
https://doi.org/10.1023/a:1009289928944

Abstract

With a view to using bile acids as shuttles for delivering platinum-related cytostatic drugs to liver tumors, a chenodeoxycholylglycinato(CDCG)-derivative of platinum(II) has been synthesized. The...

Keywords

HYDROLYSIS
SODIUM
PLATINUM
NACL
CYTOSTATIC
COMPOUNDS
CDCG
BAMET
AQUATIONS

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