Differential diagnosis of motoneurone disease from other neurological conditions.

  • 27 September 1986
    • journal article
    • Vol. 2  (8509) , 731-3
Abstract
Analysis of 422 patients with clinical diagnoses of motoneurone disease (MND), multiple sclerosis, cervical spondylosis with myelopathy, or stroke, from two referral centres, suggested a simple four-step algorithm for diagnosing MND. The algorithm provided a 98% sensitivity (true positive diagnosis) and 86% specificity, and therefore gives a baseline for diagnostic criteria suitable for use in clinical research of MND.

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