Abstract
Intracerebral inoculation of epidemic keratoconjunctivitis [ EK] virus caused a fatal encephalitis in rabbits and guinea pigs whereas inoculation of St. Louis encephalitis [SLE] virus caused a non-fatal pyrexia in guinea pigs and elicited no response in rabbits. Mice were equally susceptible to both viruses while rats were refractory. Guinea pigs recovered from EK infection were also immune to SLE and those animals recovered from SLE were immune to EK. Rabbits convalescent from SLE were immune to EK, but the reverse expt. could not be done. Although EK immune mice resisted SLE, the reverse was not completely true.

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