Case Studies on Second-Generation Anticoagulant Rodenticide Toxicities in Nontarget Species
Open Access
- 1 January 1989
- journal article
- research article
- Published by SAGE Publications in Journal of Veterinary Diagnostic Investigation
- Vol. 1 (1) , 66-68
- https://doi.org/10.1177/104063878900100118
Abstract
Specimens from 10 cases of second-generation anticoagulant rodenticide poisoning in dogs and cats were submitted to the Texas Veterinary Medical Diagnostic Laboratory during 1986 and 1987. The clinical signs most frequently observed were lethargy, dyspnea, and ventral hematomas; common necropsy findings included hemoperitoneum, hemothorax, and pulmonary hemorrhage. In the instances when histopathological examination of the tissue was done, it supported a diagnosis of coagulopathy. The presence of anticoagulants in serum or liver was confirmed by high pressure liquid chromatography, gas chromatography/mass spectrometry, or a combination of the two. Five cases of brodifacoum poisoning, 2 of bromadiolone, and 3 of diphacinone toxicity were verified. Concentrations of these rodenticides ranged from approximately 0.001 to 12 ppm.Keywords
This publication has 1 reference indexed in Scilit:
- Determination of chlorophacinone and diphenadione residues in biological materialsJournal of Agricultural and Food Chemistry, 1975