Correlations between anti‐albumin antibodies and HBsAG in hepatic patients
- 1 January 1977
- journal article
- research article
- Published by Wiley in Journal of Medical Virology
- Vol. 1 (1) , 29-34
- https://doi.org/10.1002/jmv.1890010106
Abstract
A new category of autoantibodies ‐ antipolymerized albumin antibodies (AAA) ‐ was discovered in 1974. Studies performed from 1974 to 1976 showed their diagnosis and prognostic values in hepatic diseases; the AAA tests [immunodiffusion (ID) and hemagglutination (HS)] made possible a good estimation of the total liver cell function. Without being specific for a viral hepatitis B infection, highly significant linear correlations were found for AAA precipitin and agglutinin positivities with presence of HBsAg. High titre of AAA agglutinins unaccompanied by a positive ID test, characterise the “healthy carrier” of the HBsAg, while the isolated AAA positivity in ID is met in more severe, long‐standing hepatic diseases.Keywords
This publication has 10 references indexed in Scilit:
- HBsAg ON CELL MEMBRANE IN SYMPTOM-FREE CARRIERThe Lancet, 1975
- A New Antigen-Antibody SystemPublished by American Medical Association (AMA) ,1975
- Antibodies to Human Albumin in Cirrhotic SeraJournal of Clinical Investigation, 1974
- Antibody to Hepatitis B Core AntigenNew England Journal of Medicine, 1974
- Evidence for a Role of the Microtubular System in the Secretion of Newly Synthesized Albumin and Other Proteins by the LiverJournal of Clinical Investigation, 1974
- Local hemolysis plaque assay using a new method of coupling antigens on sheep erythrocytes by glutaraldehydeImmunochemistry, 1974
- Liver morphology in acute viral hepatitis related to the hepatitis B antigenJournal of Clinical Pathology, 1972
- Smooth-Muscle Autoantibodies, Viral Infections and Malignant DiseaseProceedings of the Royal Society of Medicine, 1972
- Immunelektrophoretischer Nachweis von ?Hepatitis-Associated-Antigen? (Au/SH-Antigen)Klinische Wochenschrift, 1970