Abstract
Anterior hypothalamic temperature and intra-cranial thermal gradients were measured in anesthetized (chloralose-urethan), tracheotomized cats with intact upper respiratory pathways and when respired air was diverted from normal nasopharyngeal-buccal avenues. Additional experiments on intact, unanesthetized animals support the concept that the diencephalic-visceral temperature gradient is increased during both normal respiration and panting as a direct effect of convective and evaporative heat exchange from the upper respiratory surfaces. It is suggested that when the role of hypothalamic temperature is evaluated as a biothermal control system input, artifactual influences exerted by passive respiratory heat exchange mechanisms must be recognized.

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