Thyroid hormone components are expressed in three sequential waves during development of the chick retina
Open Access
- 14 October 2008
- journal article
- Published by Springer Nature in BMC Developmental Biology
- Vol. 8 (1) , 101
- https://doi.org/10.1186/1471-213x-8-101
Abstract
Thyroid hormone (TH) is an important developmental regulator in many tissues, including the retina. TH is activated locally via deiodinase 2 (Dio2), and it is destroyed by deiodinase 3 (Dio3). The TH receptors, TRa and TRb, mediate TH activity through hormone and DNA binding, and interactions with transcription regulators.Keywords
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