ACCEPTANCE OF A VITREOUS CARBON ALLOPLASTIC MATERIAL, PROPLAST, IN THE RABBIT EYE

  • 1 January 1980
    • journal article
    • research article
    • Vol. 19  (2) , 182-191
Abstract
Proplast, a vitreous, carbon-Teflon, fluorocarbon polymer, was tested in rabbits for corneal tolerance and acceptance. Toxicity, vascularization, epithelialization, infection and extrusion were studied clinically and histologically. Implantation of irregular-shaped pieces of material in an interlamellar corneal pocket, lamellar graft implantation with 1 exposed surface, full-thickness corneal implants in a manner similar to penetrating keratoplasty and full-thickness implants covered by a conjunctival flap were used. Proplast apparently allows fibrovascular ingrowth and stabilization without a significant foreign body response or encapsulation for a period of observation from 6 wk-4 mo. Evidence of epithelial coverage and epithelial ingrowth was found. Coverage of the Proplast with conjunctiva or corneal tissue was essential to prevent extrusion and infection.

This publication has 0 references indexed in Scilit: