Medicinal Drug Residues in Broiler Litter and Tissues from Cattle Fed Litter

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Abstract
Broiler litter samples were obtained from several houses in the main broiler producing areas of Virginia and were analyzed for oxytetracycline, chlortetracycline, penicillin, neomycin, zinc bacitracin, nicarbazin, amprolium, arsenic and copper. Residues of all drugs were detected with the exception of neomycin and zinc bacitracin. There was considerable variation in the levels of residues detected for all drugs. Longissimus muscle, liver and kidney fat samples were collected from cattle in two trials, in which litter was fed. Chlortetracycline, amprolium, nicarbazin, arsenic and copper assays were conducted on these samples. Low-level chlortetracycline residues were observed in kidney fat from 3 of 20 animals fed litter, and all other samples were negative. There was a trend for arsenic residues in muscle and liver to increase as the amount of litter fed increased. Copper was shown to accumulate in the liver as a result of feeding broiler litter. No residues of amprolium or nicarbazin were detected. From this study it appears that drug residues are frequently found in broiler littler but feeding litter to cattle resulted in little or no drug accumulation in tissues tested after a 5-day withdrawal of litter. Copyright © 1975. American Society of Animal Science . Copyright 1975 by American Society of Animal Science.

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