THE ARTIFICIAL INDUCTION OF SUBCUTANEOUS NODULES IN PATIENTS WITH RHEUMATIC FEVER 1
Open Access
- 1 January 1937
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 16 (1) , 125-128
- https://doi.org/10.1172/jci100830
Abstract
The injection of the patient''s own blood into the subcut. tissues of subjects with rheumatic fever frequently resulted in the appearance of subcut. nodules in the area injected. These nodules are clinically indistinguishable from nodules occurring spontaneously. In 90% of these patients injected who had clinical rheumatic fever these induced nodules appeared. They resulted in 50% of those patients with only laboratory evidence of active rheumatic fever. In 14% of the injected inactive rheumatic fever patients, and in 14% of those patients with chorea, nodules resulted. In only one instance (3%) did such a nodule appear in the control group studied. Hence, these nodules are seen to be produced in proportion to the severity of rheumatic fever.Keywords
This publication has 1 reference indexed in Scilit:
- THE PATHOLOGY OF SPONTANEOUS AND INDUCED SUBCUTANEOUS NODULES IN RHEUMATIC FEVER 1Journal of Clinical Investigation, 1937