Inhibitors of sterol synthesis. Differential effects of 14 alpha-hydroxymethyl-5 alpha-cholest-7-ene-3 beta, 15 alpha-diol and 14 alpha-hydroxymethyl-5 alpha-cholest-6-ene-3 beta, 15 alpha-diol on sterol synthesis in cell-free homogenates of rat liver.
Open Access
- 1 August 1981
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 256 (15) , 8085-8091
- https://doi.org/10.1016/s0021-9258(18)43392-3
Abstract
No abstract availableThis publication has 40 references indexed in Scilit:
- Possible mechanisms of demethylation of 14.alpha.-methyl sterols in cholesterol biosynthesisJournal of the American Chemical Society, 1980
- Enzymatic isomerization (Δ7 → Δ8) of the nuclear double bond of 14α-alkyl substituted sterol precursord of cholesterolBiochemical and Biophysical Research Communications, 1980
- Inhibition of sterol biosynthesis by 14α-hydroxymethyl sterolsBiochemical and Biophysical Research Communications, 1978
- Sterol synthesis. Chemical synthesis, structure determination and metabolism of 14?-methyl-5?-cholest-7-en-3?, 15?-diol and 14?-methyl-5?-cholest-7-en-3?, 15?-diolChemistry and Physics of Lipids, 1978
- Inhibition of sterol synthesis in L cells by 14α-ethyl-5α-cholest-7-en-15α-ol-3-one at nanomolar concentrationsBiochemical and Biophysical Research Communications, 1977
- Concerning the role of 4.beta.-methyl sterols in cholesterol biosynthesisJournal of the American Chemical Society, 1975
- Enzymatic conversion of 14α-methyl-cholest-7-en-3β,15ξ-diol to cholesterolBiochemical and Biophysical Research Communications, 1970
- ErrataSteroids, 1968
- Halonium ylides. IJournal of the American Chemical Society, 1968
- Cholesterol and Companions. VII. Steroid DibromidesJournal of the American Chemical Society, 1953