Characterization of a pilot plant airlift tower loop bioreactor. I: Evaluation of the phase properties with model media
- 5 June 1991
- journal article
- research article
- Published by Wiley in Biotechnology & Bioengineering
- Vol. 38 (1) , 43-55
- https://doi.org/10.1002/bit.260380107
Abstract
Investigations were carried out in a 9 m high, 4 m3 volume, pilot plant airlift tower loop bioreactor with a draft tube. The reactor was characterized by measuring residence time distributions of the gas phase using pseudostochastic tracer signals and a mass spectrometer and by evaluating the mixing in the liquid phase with single‐pulse tracer inputs. The local gas holdup and the bubble size (piercing length) were measured with two‐channel electrical conductivity probes. The mean residence times and the intensities of the axial mixing in the riser and downcomer and the circulation times of the phases as well as the fraction of the recirculated gas phase were evaluated. The gas holdup in the riser is nearly uniform along the reactor. In the downcomer, it diminishes from top to bottom. The liquid phase dispersion coefficients, DL, are smaller than those measured in the corresponding bubble columns. In the pilot plant with tap water the following relationship was found: DLr = cw; with c = 203.4; n = 0.5;DLr(cm2 s−1;) and WSG(cm s−1) where DLr is the longitudinal dispersion coefficient in the riser and WSG is the superficial gas velocity. The gas phase dispersion coefficients in the riser of the pilot plant, DGr, are also enlarged with increasing superficial gas velocity, WSG, however, no simple relationship exists. Parameter DGr is the highest in the presence of antifoam agents, intermediate in tap water, and the smallest in ethanol solution.Keywords
This publication has 7 references indexed in Scilit:
- NewsAvian Pathology, 1987
- Characterization of Bioreactors by Mass Spectrometry AnalysisPublished by Springer Nature ,1987
- Tracer dispersion in loop reactorsChemical Engineering Science, 1985
- Tracer dispersion in a laboratory air-lift reactorChemical Engineering Science, 1983
- Loop reactorsPublished by Springer Nature ,1979
- Bestimmung der Gasphasen‐Dispersion in Blasensäulen mit Hilfe der FrequenzganganalyseChemie Ingenieur Technik - CIT, 1978
- Mixing and mass transfer in tall bubble columnsChemical Engineering Science, 1974