IMMUNITY FOLLOWING THE INJECTION OF MONKEYS WITH MIXTURES OF POLIOMYELITIS VIRUS AND CONVALESCENT HUMAN SERUM
Open Access
- 1 January 1931
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 53 (1) , 115-121
- https://doi.org/10.1084/jem.53.1.115
Abstract
1. Experiments are reported on the use of poliomyelitis virus neutralized by specific antiserum as an agent to induce active immunity against the experimental disease in monkeys. 2. The results indicate that protection can be conferred upon a certain number of the treated animals. 3. The neutralized material gave rise in no instance to symptoms of disease in the treated monkeys. 4. Active poliomyelitis virus, suitably neutralized by admixture with convalescent serum, was without pathogenic effect when given by repeated nasal instillations.Keywords
This publication has 1 reference indexed in Scilit:
- INTRADERMAL VERSUS SUBCUTANEOUS IMMUNIZATION OF MONKEYS AGAINST POLIOMYELITISThe Journal of Experimental Medicine, 1929