A Synthetic Approach to (+)-Dioncophylline C
- 1 January 1995
- journal article
- Published by CSIRO Publishing in Australian Journal of Chemistry
- Vol. 48 (12) , 2013-2021
- https://doi.org/10.1071/ch9952013
Abstract
In a synthetic approach to (+)-dioncophylline C (1), a coupling between the chiral oxazoline (3) and the Grignard reagent obtained from bromide (4) gave the major biaryl (5) and the minor biaryl (12) in good yield and high diastereoselectivity (yield 70%; ratio 91:9). The stereochemistry of the major biaryl (5) was confirmed by X-ray structure analysis of the derived crystalline iodide salt (13).Keywords
This publication has 0 references indexed in Scilit: