Substituted Methyl 5β-Cholan-24-oates; Part III: Synthesis of a Novel Cholaphane from Ethylene Glycol Diester of Lithocholic Acid by Cyclization with Terephthalic Acid

Abstract
A novel cholaphane, containing both an aliphatic and an aromatic spacer, has been prepared from ethylene glycol diester of 3α-hydroxy-5β-cholan-24-oic acid (lithocholic acid) by cyclization (Yamaguchi method) with terephthalic acid.

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