Abstract
Matched groups of men (2) aged 20-25, 20 with relatives (usually father or brother) who were alcoholics and 20 with no family history of alcoholism (controls), were given 0.75 ml of alcohol per kg of body weight and asked to rate themselves on the Subjective High Assessment Scale (SHAS). The subjects felt less intoxicated and showed less emotional response than did the controls on 22 of 38 SHAS items. Blood alcohol concentrations (BAC) did not differ significantly between groups when examined by multiple points analysis of variance for the entire 180 min experimental period, but when analyzed at single times the subjects'' BAC was significantly lower than controls'' at 60 min (0.074 vs. 0.087%; P < .05).