INTRAOCULAR AXONAL SWELLING PRODUCED BY PARTIAL, IMMEDIATELY RETROBULBAR LIGATURE OF OPTIC-NERVE

  • 1 January 1977
    • journal article
    • research article
    • Vol. 16  (6) , 537-541
Abstract
An experimental intraorbital ligature produced papilledema characterized by axonal swelling and accumulation of mitochondria in the lamina retinalis of the optic disc of rhesus monkeys [Macaca mulatta] subjected to immediately retrobulbar ligature of a portion of the optic nerve. This is an improved technique for investigating the pathogenesis of papilledema and optic neuropathy.