The Use of High Intensity Ultrasound in Experimental Neurology

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Abstract
The results of a histological study of the changes produced by high intensity ultrasound on tissue of the central nervous system are presented. The study was restricted to the nontemperature effects of the sound since these are of particular significance for neurology. The results obtained show that nerve cell bodies are particularly sensitive to the action of the ultrasound, while blood vessels and nerve fibers are much more resistant. The use of a focused beam of ultrasound to produce discrete lesions deep in the brain without disturbance of the vascular system or through‐going nerve tracts in the region of the lesion is demonstrated by a study on the bulboreticular inhibitor formation of the cat medulla. Physical factors which require consideration are discussed in terms of the histological work.