Morphological changes in Plasmodium cynomolgi following proguanil, sulphadiazine, and mepacrine therapy
- 1 June 1951
- journal article
- research article
- Published by Oxford University Press (OUP) in Transactions of the Royal Society of Tropical Medicine and Hygiene
- Vol. 44 (6) , 707-716
- https://doi.org/10.1016/0035-9203(51)90007-7
Abstract
P cynomolgi stages in which the chromatin had begun to divide have their regular cycle modified by proguanil and sulphadiazine. These changes end in complete degeneration of the organisms except in resistant strains, in which degeneration is arrested before complete disintegration occurs. Other stages in the life cycle of the parasite were not visibly altered. After treatment with mepacrine the changes are mainly cytoplasmic, being particularly marked in the ring and ameboid trophozoite stages.Keywords
This publication has 4 references indexed in Scilit:
- Some observations on the action of quinine, atebrin, and plasmoquine on Plasmodium vivaxTransactions of the Royal Society of Tropical Medicine and Hygiene, 1949
- Observations on the action of paludrine on malarial parasitesTransactions of the Royal Society of Tropical Medicine and Hygiene, 1947
- The effect of anti-malarial drugs on Plasmodium falciparum (New Guinea strains) developing in vitroTransactions of the Royal Society of Tropical Medicine and Hygiene, 1946
- The shute method of making preparations of ex-flagellating gametocytes and oökinetes of malarial parasitesTransactions of the Royal Society of Tropical Medicine and Hygiene, 1934