Long-term patency of the ductus arteriosus after balloon dilatation: an experimental study.

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Abstract
Balloon dilatation of the ductus arteriosus was carried out in vivo in 8 piglets that were 12-16 days old. The ductus was functionally closed in all animals before dilatation. Long-term patency for periods of up to 6 mo. after the procedure was demonstrated in 6 animals by angiography, Doppler ultrasound examination and at autopsy. The presence of hemodynamically significant shunts was indicated by clinical development of heart failure, pulmonary infections and left ventricular hypertrophy. These results confirm the value of this laboratory preparation to create left-to-right shunts at the ductus level.

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