On the role of planar chirality: a tunable enantioselectivity in palladium-catalyzed allylic alkylation with planar chiral 1,1′-P,N-ferrocene ligands

Abstract
A series of planar chiral 1,1′-P,N-2′-substituted ferrocene ligands 9–12 and 16, prepared with diastereopurity >99∶1, have been used to examine the role of planar chirality, and significant effects on enantioselectivity as well as the control of absolute configuration in palladium-catalyzed allylic alkylation as a model reaction were observed.

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