Cervical Chlamydia trachomatis and mycoplasmal infections in pregnancy. Epidemiology and outcomes

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Abstract
In a prospective study of chlamydial and mycoplasmal infections in pregnancy, C. trachomatis occurred in 8.0%, Mycoplasma hominis in 23.5% and Ureaplasma urealyticum in 72.3% of 1365 enrollees. By multivariate analysis, C. trachomatis was correlated with lower socioeconomic status, age .ltoreq. 23 yr and .ltoreq. 12 yr of schooling. U. urealyticum was correlated with age and lower socioeconomic status. M. hominis was correlated with > 1 recent sexual partner, 1st intercourse at age 17 years or younger and higher socioeconomic status. These cervical infections did not predict low birth weight, abortion, stillbirth, prematurity or premature rupture of membranes. Only M. hominis predicted endometritis/fever after vaginal delivery (relative risk, 7.3). IgM-seropositive C. trachomatis-infected women had more low-birth weight infants and more premature rupture of membranes than IgM-negative C. trachomatis-infected women or C. trachomatis culture-negative women. Thus, only certain subgroups of infected women may experience adverse pregnancy outcomes.