Mycobacterium tuberculosis H37Rv3377c encodes the diterpene cyclase for producing the halimane skeleton
- 1 January 2005
- journal article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 8,p. 1016-1018
- https://doi.org/10.1039/b415346d
Abstract
The cloning and functional expression of Mycobacterium tuberculosis Rv3377c in Escherichia coli revealed that this gene encodes the diterpene cyclase for producing (+)-5(6),13-halimadiene-15-ol, which accepts geranylgeranyldiphosphate as the intrinsic substrate.Keywords
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