Reduction of 51Cr-Permeability of Tissue Culture Cells by Infection with Herpes Simplex Virus Type l

Abstract
Infection of different tissue culture cells [human laryngeal HEp-2, cervical carcinoma HeLa, amnion FL, liver chang and oral carcinoma KB, primary chick embryo fibroblast and rabbit kidney, mouse fibroblast L and baby hamster kidney BHK-21] with herpes simplex cirus type 1 (HSV-1) resulted in a reduced 51Cr-permeability. A stability of the cellular membrane to Triton X-100, toxic sera and HSV-specific complement-mediated immune-cytolysis could be observed simultaneously. The results differed with respect to the cell strain used in the experiments.

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